While I find their choice of names interesting, TokBox (as in "talk" box with a funny accent) is a newly updated video conferencing service with the tremendous benefit of NOT requiring the installation of software in order to get started. They just updated the service to allow for 6-way conferencing. The interface is mostly written in Flash and one can assume that any webcam your computer's operating system recognizes will also be recognized by TokBox. Meebo is required for 6-way conferencing but the service as a stand alone product warrants the 'ole tip of the hat for just being so darn cool.
Here is some more information from their blog.